Hotel Twenty One
Via Cola Di Rienzo 23,, Vaticano Prati, 00192, Italy
Book online now . Rates from EUR57.
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US: 888-205-7322
UK: 0808 145-3778
EU: +1 469-610-3608
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1 Room With 2 Adults Change Search
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Rates from EUR 57
Twentyone Hotel is a modern 4-star hotel located on one of Rome’s finest shopping streets. Castel Sant’Angelo as well as the historic centre is only a 10-minute walk away.

Perfectly situated on Via Cola di Rienzo, this boutique hotel of luxury allows guests to explore the stylish Prati district, home of Saint Peter’s Basilica and the Vatican, with ease. Bus and metro links are found close by.

Guests of Twentyone Hotel will enjoy its ultra-modern interiors and minimalist décor. Each of the spacious guestrooms comes with an LCD satellite TV. Guests can also take advantage of free Wi-Fi access in the lounge.

The Friendly staff of Twentyone will be pleased to arrange transfers, trips and guided tours and for guests.

Hotel Services and Facilities

Free WiFi Free parking Free breakfast

Hotel facilities

  • 24 hour front desk
  • Airport Transportation
  • Attraction Shuttle Service
  • Concierge
  • Dry cleaning service
  • Internet Access - Free Public Access
  • Laundry
  • Non-Smoking Facility
  • Parking - Self
  • Restaurant
  • Room Service
  • Wheelchair Access

Guest reviews

Click here to leave your opinion >>
stayed in July, 2009
Guest Score 7.5 out of 10
The location. The clean and new decoration of the hotel.
No 24h room service; no restaurant or living room. The breakfast was only continental.Some of the employers had difficulty to speak english.

How to book

Making your reservation in Hotel Twenty One is easy and secure. Simply select your dates of stay and click on the “Check Rates” button to submit the form.

After room types and rates are returned to your screen, you will be able to choose the rate you desire by reading the room information in the center of the screen, then clicking on the "Book Now" button on the right side of the screen. After you have selected your desired room type, you will be taken to a "Complete your booking" form. Then you will need to review the "Details of your stay" and fill in the blanks on the "Guest Details" section. Be sure your name and email address are spelled correctly.

After you fill out all of the needed information, press the "Complete reservation" button. To ensure your security, we use a secure commerce server, which encrypts the credit card number and encodes it into a non-usable form.

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Guest reviews
...clean and new decoration of the hotel...
Overall score: 7.5
(out of 10) Based on 1 votes
Click here to leave your opinion

Area information

    • Rome, Italy (CIA-Ciampino) - 9.84 mi
    • Rome, Italy (FCO-Leonardo Da Vinci) - 13.69 mi
    • Museum of the Souls of Purgatory - 0.38 mi
    • Castel Sant'Angelo Museum - 0.46 mi
    • Explora il Museo dei Bambini di Roma - 0.49 mi
    • Altemps Museum - 0.59 mi